If you recognize yourself in one or more of these situations, the problem surely does not come from you, but from your intestines. And while we talk a lot about the intestinal microbiota, and how essential it is to preserve it, it is not this reason that will be mainly discussed today. Indeed, restoring the integrity of your microbiota is essential if you want to regain intestinal comfort and general well-being. But if the environment in which bacteria live is not healthy, they will never be able to provide all their benefits effectively. The integrity of your intestinal wall is likely the reason you're struggling to achieve your wellness goals, so let's try to get a closer look.
How can the intestinal wall hinder your quest for well-being?
You should know that the intestinal wall is actually a barrier. It is supposed to provide a measured connection between the outside world and the internal environment of your body. Its main function: to guarantee appropriate isolation of unwanted contents of the food bolus, while maintaining nutrient absorption capacities. Because yes, our intestines are confronted with all types of harmful molecules: toxins, pro-inflammatory molecules, pathogens... But they know how to defend themselves. In fact, the pores found all along this organ are of such a size that they do not allow these harmful molecules, which are too large, to pass through. But they are still large enough to allow nutrients, much smaller molecules, to pass through and then pass them throughout the body through the blood circulation.
However, there are many risk factors that impact the configuration of the intestinal wall. Alcohol, stress, infections, under/malnutrition, immune deficiency, treatments, dysbiosis... They all contribute to the relaxation of pores which will become larger, allowing toxins to travel freely throughout your body. This phenomenon has a name, it is intestinal porosity, or intestinal hyperpermeability, it is often characterized as “leaky gut syndrome”.
How is this a hindrance for me?
No matter how much we try to preserve a varied microbial population within our intestines, our bacteria will only be able to work well in a healthy environment. This is often the reason why some people do not see any improvement in their digestive problems after a course of probiotics . Intestinal wall and microbiota go hand in hand, and if we want to maximize our well-being over time, it is essential to preserve them individually so that they work correctly together.
For people who want to lose weight, it is also wise to ensure the health of your intestinal barrier. Indeed, intestinal porosity often induces dysbiosis, but a microbial imbalance is deleterious for the processing and assimilation of nutrients. This factor disrupts macronutrient metabolism and leads to dietary deficiencies. But by accumulating toxins, we further slow down weight loss, because this causes an overload of the liver and other emunctory organs. They work poorly, slow us down and make us tired, two factors that are harmful to the motivation necessary for lasting weight loss. They also degrade our digestion abilities, and there we have a vicious circle.
How to cure it ?
Unfortunately, it is very complicated to verify that you are indeed subject to intestinal porosity. But as we are all faced with risk factors, we are all weakened, and not seeing any improvement in our condition by multiplying solutions is a major sign.
To improve the situation, at DIJO we have created the regenerated intestine pack for:
- Strengthen its intestinal wall by giving it its favorite food: glutamine! This amino acid is the preferred fuel for those involved in our intestinal barrier. If food provides part of it, supplementation remains the simplest and most effective solution. Indeed, studies have shown that one gram of glutamine per day helps restore the intestinal wall. DIJO has created its Glutamine treatment concentrating 3 g per dose, to ensure its effectiveness and best restore the most damaged walls.
- Complete with a course of probiotics for strong intestines! The essential probiotics concentrates 8 strains and 28 billion CFU per dose to promote better digestion, a robust immune system, easy weight regulation, improved morale and clearer skin.
To find out more, you can also consult our articles “ What is intestinal porosity? ” and “ The intestinal wall: an essential barrier to preserve ”.
Sources:
[1] Fukui H. (2016). Increased Intestinal Permeability and Decreased Barrier Function: Does It Really Influence the Risk of Inflammation?. Inflammatory intestinal diseases , 1 (3), 135–145. https://doi.org/10.1159/000447252
[2] Fink MP (2003). Intestinal epithelial hyperpermeability: update on the pathogenesis of gut mucosal barrier dysfunction in critical illness. Current opinion in critical care , 9 (2), 143–151. https://doi.org/10.1097/00075198-200304000-00011
[3] Li, M., Oshima, T., Ito, C., Yamada, M., Tomita, T., Fukui, H., & Miwa, H. (2021). Glutamine Blocks Interleukin-13-Induced Intestinal Epithelial Barrier Dysfunction. Digestion , 102 (2), 170–179. https://doi.org/10.1159/000502953
[4] Maldonado Galdeano, C., Cazorla, SI, Lemme Dumit, JM, Vélez, E., & Perdigón, G. (2019). Beneficial Effects of Probiotic Consumption on the Immune System. Annals of nutrition & metabolism , 74 (2), 115–124. https://doi.org/10.1159/000496426