What you must remember :
- N-Acetylglucosamine is a major component of skin, cartilage and tendons.
- N-Acetylglucosamine is known to soothe pain related to joint disorders
- N-Acetylglucosamine reduces imperfections, hyperpigmentation and fine lines to restore an even and radiant complexion.
- N-Acetylglucosamine is known for its anti-inflammatory properties, capable of improving joint health and skin disorders such as acne.
What is N-Acetylglucosamine?
N-Acetylglucosamine (or NAG) is an amino sugar composed of an acetyl group, making it more easily assimilated by the body. Its polymerization forms chitin, a molecule naturally present in the shell of certain crustaceans and insects.
N-Acetylglucosamine is a direct precursor ofhyaluronic acid , naturally present in the various tissues of the body, particularly in the dermis. Hyaluronic acid is a real “water sponge”, perfectly natural which ensures hydration and allows the skin to maintain its radiance and softness.
Benefits of N-Acetylglucosamine
Due to its composition, N-Acetylglucosamine plays a crucial role in the strengthening and structure of joints as well as in the hydration and firmness of the skin.
N-Acetylglucosamine and joints
N-Acetylglucosamine is a key element in the formation of cartilage, tendons and the synovial fluid that lubricates joints. It is mainly known for soothing pain related to joint disorders and for its anti-inflammatory properties in joint inflammatory phenomena. Studies suggest that oral N-Acetylglucosamine supplementation can help reduce pain, strengthen joint mobility, and reduce the risk of osteoarthritis.
N-Acetylglucosamine and skin
Studies have shown that supplementation with N-Acetylglucosamine, taken orally, improves the general condition of the skin .
N-Acetylglucosamine helps to reduce skin spots by inhibiting the production of melanin, the skin pigment, thus illuminating the dark areas of the face to provide a more uniform and radiant complexion. Additionally, its anti-inflammatory properties allow it to treat various inflammatory skin disorders, including acne .
N-Acetylglucosamine precursor of hyaluronic acid
Being the direct precursor ofhyaluronic acid , naturally present in the dermis, N-Acetylglucosamine promotes water retention in the skin . Indeed, this large molecule that is hyaluronic acid can retain up to 1000 times its weight in water. Thanks to its humectant power, it ensures optimal hydration and allows the skin to maintain its radiance, firmness and elasticity.
With age, the body's production ofhyaluronic acid tends to gradually drop. It is therefore interesting to formulate a unique product which provides both hyaluronic acid and its precursor, in order to boost their effects. In fact, taking N-Acetylglucosamine orally allows us to considerably increase the stocks of hyaluronic acid, naturally present in our body. The advantage of oral supplementation compared to skin care is that it gives our body the choice to dispose of its stock of hyaluronic acid as it sees fit, in order to send it to the tissues that need it. most needed (skin, hair or joints).
Indications and dosage of N-Acetylglucosamine
It is found in many supplements in the form of powder, tablets or capsules.
Taking N-Acetylglucosamine is contraindicated in children under 12 years of age and pregnant and breastfeeding women. It is also common in people allergic to shellfish, suffering from acute tissue inflammation, an autoimmune disease or cancer. If you are taking medical treatment, it is important to seek advice from your doctor before taking supplements.
At present, there is no official dosage to obtain benefits, but scientific studies identify doses ranging from 500mg to 1000mg. If the dosage is respected, N-Acetylglucosamine does not cause any unwanted side effects. However, in high doses, it can cause nausea and stomach aches.
Bring N-Acetylglucosamine to your body thanks to DIJO
At DIJO, we are committed to supporting you in your well-being care routines. This is why we developed Focus Peau , a product based on prebiotics and compounds essential for maintaining the beauty of the skin .
Beyond the skin, which benefits from the many benefits of our product based on marine collagen ,hyaluronic acid combined with its precursorN-Acetylglucosamine , the joints and all the connective tissues that surround them, such as cartilage, are find them reinforced.
Whether to improve skin hydration, reduce imperfections, reduce the first signs of aging or strengthen joint mobility, this Rejuvenation treatment offers you a natural approach for your overall well-being.
Sources :
[1] Chen, JK, Shen, CR, & Liu, CL (2010). N-acetylglucosamine: production and applications. Marine drugs , 8 (9), 2493-2516.
[2] Kubomura, D., Ueno, T., Yamada, M., Tomonaga, A., & Nagaoka, I. (2017). Effect of N-acetylglucosamine administration on cartilage metabolism and safety in healthy subjects without symptoms of arthritis: A case report. Experimental and Therapeutic Medicine , 13 (4), 1614-1621.
[3] Połubinska, A., Cwalinski, J., Baum, E., & Bręborowicz, A. (2013). N‐Acetylglucosamine modulates function of the skin fibroblasts. International Journal of Cosmetic Science , 35 (5), 472-476.
[4] Wang, ST, Neo, BH, & Betts, RJ (2021). Glycosaminoglycans: sweet as sugar targets for topical skin anti-aging. Clinical, cosmetic and investigational dermatology , 1227-1246
